This topic area focuses on the effectiveness of interventions designed to improve the health, safety, or employment outcomes for people with Substance Use Disorder (SUD), as well as those that contribute to building a behavioral health workforce to provide treatment for SUD and to support recovery efforts. CLEAR conducted a review of evidence on the topic, drawing on two DOL-funded literature reviews: Workers’ Compensation and the Opioid Epidemic: State of the Field in Opioid Prescription Management and The Role of the Workforce System in Addressing the Opioid Crisis: A Review of the Literature.